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Genetic survey exposes flaws in widely used mouse models
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Genetic survey exposes flaws in widely used mouse models

www.nature.com·Callaway, Ewen·18 days ago
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A survey of more than 300 mouse strains has found widespread discrepancies between how mutant mice are reported and their actual genetic make-up.…

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Long-term editing of brain circuits using an engineered electrical synapse
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Long-term editing of brain circuits using an engineered electrical synapse

Nature·Dzirasa, Kafui·19 days ago
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Electrical signalling across distinct populations of brain cells underpins cognitive and emotional function. However, approaches that selectively regulate electrical signalling between two cellular components of a mammalian neural circuit remain sparse.…

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Eosinophils drive intestinal remodelling and innate defence in reproduction
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Eosinophils drive intestinal remodelling and innate defence in reproduction

Nature·Lim, Ai Ing·19 days ago
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Mammalian reproduction requires substantial immune adaptations to safeguard reproductive success and to ultimately shape the evolutionary trajectories of a species.…

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An X-linked long non-coding RNA, PTCHD1-AS, and the core features of autism
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An X-linked long non-coding RNA, PTCHD1-AS, and the core features of autism

Nature·Scherer, Stephen W.·19 days ago
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There are around 100 genes or copy-number variations used in genetic testing for autism spectrum disorder (ASD)1,2. The established genes are protein coding, and the associated phenotypes usually extend beyond sociobehavioural traits seen in autism,…

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See 17 Intricate Microscope Photographs That Make the Miniature World Immense. They Won the Evident Image of the Year Contest
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See 17 Intricate Microscope Photographs That Make the Miniature World Immense. They Won the Evident Image of the Year Contest

Smithsonian Magazine·Carlyn Kranking·19 days ago
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#animals#brain#fish#insects#mice#evident

The sixth annual competition showcases scientific microscopic imaging, illuminating tiny parts of nature, from individual cells to arthropods, diatoms and a zebrafish brain

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Stunning fossil discovery challenges the origins of animal life
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Stunning fossil discovery challenges the origins of animal life

ScienceDaily·ScienceDaily·20 days ago
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Scientists revisiting mysterious 540-million-year-old microfossils from Brazil have overturned a major idea about early animal life. What were once thought to be trails left behind by tiny worm-like creatures are now believed to be fossilized communities…

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These Singing Mice Squeak Back and Forth—and Don't Interrupt. Scientists Found the Brain Pathway Behind Their Impressive Songs
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These Singing Mice Squeak Back and Forth—and Don't Interrupt. Scientists Found the Brain Pathway Behind Their Impressive Songs

Smithsonian Magazine·Rudy Molinek·21 days ago
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#animals#biology#brain#evolution#mice#singing

Alston’s singing mice carry out complex vocalizations and even appear to converse politely with one another. The neural circuitry that makes this possible is simpler than researchers expected

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Scientists successfully transfer longevity gene and extend lifespan
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Scientists successfully transfer longevity gene and extend lifespan

ScienceDaily·ScienceDaily·22 days ago
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Scientists at the University of Rochester pulled off a remarkable experiment: they transferred a longevity-related gene from the famously long-lived naked mole rat into mice, and the mice ended up healthier and lived longer.…

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Scientists found the “holy grail” gene that could one day help humans regrow limbs
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Scientists found the “holy grail” gene that could one day help humans regrow limbs

ScienceDaily·ScienceDaily·23 days ago
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Scientists studying axolotls, zebrafish, and mice have uncovered a shared set of genes that may one day help humans regrow lost limbs. By identifying powerful “SP genes” involved in regeneration, researchers discovered that disabling these genes stopped…

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