High estrogen in the brain's memory center may worsen one's resilience against traumatic events, swaying the tendency to develop memory problems or post-traumatic stress in the aftermath, a new study in mice suggests. The research, published in April in the journal Neuron , explored the effects of estrogen in the mouse brain. It zoomed in on the hippocampus , a key part of the brain involved in learning and memory. Both male and female mammals produce significant amounts of estrogen in the hippocampus, despite it often being framed as a "female" hormone. The study suggests that these local estrogen concentrations may influence one's vulnerability to memory problems following major acute stress. Although the research was conducted in mice, the authors think it likely has relevance to humans. "I think this is highly translatable," study senior author Dr. Tallie Z. Baram , a professor, developmental neuroscientist and child neurologist at the University of California, Irvine, told Live Science.…