A popular gym supplement could be doing squat. While some supplements have scientifically-backed benefits, not all do the heavy lifting they claim to by building muscle, enhancing power output and boosting brain performance. And the impacts of one especially popular addition to any gym-goer’s routine actually depend on three major factors. Despite its safety and popularity in the gym, one supplements effectiveness has limitations based on three major factors. Oleksandr – stock.adobe.com A naturally occurring substance in muscle cells, creatine is found in foods like red meat, fish and poultry, though many take it as a supplement. However, research published Sunday in the  Handbook of Creatine and Creatinine In Vivo Kinetics looked into the hype behind the supplement and found some limitations. While the findings, led by pharmaceutical researcher and former professor Dr. Mehdi Boroujerdi, highlight some positive effects of creatine, there are other aspects that can influence its efficiency.…