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$3 million prize goes to duo whose research led to first sickle cell CRISPR therapy

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The 2026 Breakthrough Prize was given to two researchers whose research led to a functional cure for sickle cell disease. (Image credit: Just_Super via Getty Images) Two scientists whose work ushered in the first approved therapy using the gene-editing tool CRISPR have won the $3 million Breakthrough Prize in Life Sciences. The prize winners ‪—‬ Dr. Swee Lay Thein , of the National Heart, Lung and Blood Institute (NHLBI), and Dr. Stuart H. Orkin , of Harvard University — shared the award for basic research that led to the development of a gene therapy that treats the blood disorders sickle cell disease and beta-thalassemia. The Breakthrough Prize in Life Sciences has been awarded since 2013 to recognize accomplishments in the life sciences. Deadly blood disorders Sickle cell disease affects around 7 million to 8 million people globally, predominantly in Africa.…

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