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Obesity may change how early breast cancer spreads, researchers find

The Independent·Julia Musto·3 days ago
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We’ve long known obesity leaves people at a heightened risk of disease and premature death. Now, researchers say it could also impact how early breast cancer spreads in women. Unique changes in the bodies of women with obesity are helping breast cancer to become invasive and typically more advanced, spreading into surrounding breast tissue, new Oklahoma University research says. The changes were seen in cancer tumors and the surrounding cells. The researchers discovered higher levels of an enzyme known as Sulfatase 2 in tumor cells, too. Although more work needs to be done to determine how these changes contribute to invasive breast cancer, the findings could help doctors better treat patients. “This could be why women with obesity are at higher risk for invasive breast cancer,” Bethany Hannafon, an assistant professor at the university’s College of Medicine, explained in a statement .…

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