This September, the Louisville Cardinals and Ole Miss Rebels will travel to Nashville, Tennessee, where they will meet up for a neutral site matchup. It will be the first meeting since 2021 between the two teams. In the first matcup, Ole Miss beat Louisville 43-24 in the Chick-fil-A kickoff game in Atlanta, Ga. Three key matchups to keep an eye out for come college football as both of these teams are ranked in the ESPN "way too early" top 25 power rankings, with Ole Miss being ranked 9th and Louisville 14th. Power versus Power Using a belt, Louisville Cardinals defensive lineman Clev Lubin (50) smacks a coache's whiteboard with BTA written on it after the Cards dominated rival Kentucky 41-0 Saturday, November 29, 2025 in Louisville, Kentucky. | Matt Stone/Courier Journal / USA TODAY NETWORK via Imagn Images In 2025 the Ole Miss Rebels offensive line ranked first in fewest sacks allowed in the SEC with just 19.0 in 15 games.…