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Is a ‘selfish gene’ making a Utah family have twice as many boys as girls?

Nature·@EwenCallaway·2 months ago
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Babies tend to have the same probability to be born biologically male or or female — but family genetics could skew those odds in either direction. Credit: Waltraud Grubitzsch/dpa via Alamy By sifting through an anonymized genealogy database, researchers have discovered a Utah family that has been having twice as many boys as girls for seven generations. It is the first clear evidence that humans might have ‘selfish genes’ that distort the sex ratio of offspring from roughly 50:50, the researchers argue in a preprint posted on bioRxiv earlier this month1. The findings have not been peer-reviewed. Such sex ‘distorters’ have been discovered — and studied in great depth — in laboratory animals such as mice and flies, in which their effects can be detected through selective breeding. “If you look, more often than not, you find them,” says Nitin Phadnis, an evolutionary geneticist at the University of Utah in Salt Lake City, who co-led the study.…

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