It’s that point of the offseason where many fans have taken a break from concerning themselves with the stresses associated with rooting for their favorite football team, but not fantasy football fans. Despite it being the slow part of the NFL calendar, those who both root for the Bills and play fantasy sports may be wondering what’s going to happen with James Cook in 2026, when signs are starting to point toward last year’s rushing champion experiencing a regression. It was a phenomenal season for Cook in 2025, but with a new head coach, a few new offensive pieces and other factors playing into his future in the Bills’ backfield, projecting the 26-year-old’s upcoming campaign is an intriguing proposition. Historic season Buffalo Bills running back James Cook III (4) runs the ball during the first half against the Jacksonville Jaguars.…