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How genetic information helps cells resist chaos and stay alive

phys.org·H. Lee Moffitt Cancer Center & Research Institute·about 1 month ago
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Bulletin of Mathematical Biology (2026). DOI: 10.1007/s11538-026-01636-0"> The encoded genetic information is translated into a string of amino acids. Credit: Bulletin of Mathematical Biology (2026). DOI: 10.1007/s11538-026-01636-0 A Moffitt Cancer Center researcher has introduced a new model that addresses one of biology's most fundamental questions: How does genetic information keep living systems organized and therefore alive? The Perspectives article, by Robert A. Gatenby, M.D., co-director of Moffitt's Center of Excellence for Evolutionary Therapy and lead author of the study published in the Bulletin of Mathematical Biology , speaks to a longstanding puzzle: Cells remain highly structured and functional even though physical systems naturally tend toward disorder, a process known as entropy. It is clear that cells use information in their genes to maintain order, but the general principles and specific mechanisms that allow this have never been fully explained.…

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