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Early human embryonic cells may be vulnerable to SARS-CoV-2 infection

phys.org·University of California - Riverside·about 1 month ago
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Credit: Unsplash/CC0 Public Domain A University of California, Riverside study reports that cells in the earliest stages of human development could be susceptible to infection by SARS-CoV-2, which causes COVID-19, offering new insight into how the virus interacts with developing human tissues and why that may matter for pregnancy research. Using a "disease-in-a-dish" laboratory model of early human embryonic development, researchers Ann Song and Prue Talbot examined how different cell types respond to exposure to artificial SARS-CoV-2–like particles. They found that multiple early embryonic cell types can be infected, but susceptibility varies significantly. Cells destined to become the ectoderm — the layer that eventually forms the skin and nervous system — were by far the most vulnerable.…

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