What are your thoughts about workflow tools for bioinformatics and is NextFlow truly the answer? Over my 15+ year career I’ve had to deal with workflow managers at every job. I’ve worked with custom ones, implemented multiple different ones, done the testing to select which to use. I’ve heavily customized them. Basically I have lived/breathed them for quite a while. I can write a standard NGS germline variant calling pipeline from memory because I did it so many times before a standardized pipeline emerged. The issue I have is that NextFlow seems to be winning and becoming the closest thing there is to a standard workflow tool + having nfcore is huge, but I still really don’t like using NextFlow. The main thing I’m trying to figure out/struggling with is if I should swallow my objections and use nextflow because it is becoming the standard and supporting other workflow managers will be harder in the future or if the issues I have with nextflow truly justify not using it.…