From Brennan Plaetzer: Hi Tyler, Your post yesterday argued AI will replace papers with meta-papers that synthesize, re-run, and extend prior work. I built one in oncology last month, before reading your post. I ran my friend Omar Abdel-Wahab’s (MSK) last ten papers through an AI synthesis layer. This came out on top: an integrated, falsifiable hypothesis bridging two of his 2025 papers, one in  Cancer Cell  on a refractory MEK1 mutation, one in  Cell  on splicing-derived neoantigens. It comes with seven testable experiments his lab can run today. The move generalizes to any field: surface the questions hidden in plain view, the ones the source papers could answer with their own data but never asked. https://page56capital.com/writings/cross-paper-synthesis The “box” you described already exists in biology. It just doesn’t have a name there yet.…