In order for Vmax to increase, you need to have more enzyme+substrates bound to speed up reactions If you have 5 enzymes and only 2 substrates, only 2 substrates will be bound to an enzyme and increase speed of reaction - right? If you have 5 enzymes and 5 substrates, you have reached peak speed If you have 5 enzymes and 10 substrates, you are at the same speed as scenario 2. If you add enzymes, you'll have increased speed Why does Vmax not increase if you add more substrate in scenario 1? submitted by /u/scienceeeee [link] [comments]