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DNA-reading AI reconstructs ancestry in minutes, matching top statistical methods

phys.org·Leila Okahata·28 days ago
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Proceedings of the National Academy of Sciences (2026). DOI: 10.1073/pnas.2518956123"> True versus predicted coalescence times for three inference approaches across two demographic scenarios: a constant population size and a fluctuating “sawtooth” demography. Credit: Proceedings of the National Academy of Sciences (2026). DOI: 10.1073/pnas.2518956123 Researchers at the University of Oregon have developed an artificial intelligence tool that can read genetic code the way large language models like ChatGPT read text. Scanning the genome for biological mutation patterns, the computer model traces pairs of genes back in time to their last common ancestor. It's the first language model designed for population genetics, said Andrew Kern, a computational biologist in the UO College of Arts and Sciences.…

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