Top 5 Can’t Miss Stay at Hotel Emma, a property that blends historic charm with modern luxury, top-tier amenities, and a colorful backstory. Snag a reservation at San Antonio’s first Michelin-starred restaurant, Mixtli. Grab a chispa—San Antonio's unique spin on a margarita—at El Mirasol or Soluna.  Go for a solo run by the River Walk, or join one of San Antonio's popular free run clubs. Visit the River Walk’s Selena Bridge, made famous by a Jennifer Lopez scene in the 1997 “Selena” biopic. San Antonio, the second-largest city in Texas, wears its size lightly. Wrapped in centuries of vibrant Hispanic heritage, it has the warmth of a small town and pulses with culture much deeper than the waters of the River Walk. It’s also a favorite among Travel + Leisure readers, who named it one of the best U.S. cities in the 2025 World’s Best Awards. It only takes one visit to see that San Antonio is far more than just the home of the Alamo.…