A gentler treatment for children whose leukaemia has come back could boost survival and quality of life, a Great Ormond Street study has found. The new regime reduces the need for intensive chemotherapy and eliminates deaths linked to treatment in children with relapsed leukaemia . Led by doctors at Great Ormond Street Hospital (Gosh), the UKALL Rel2020 study found that children and young people with relapsed acute lymphoblastic leukaemia (ALL) can be treated safely with significantly less intensive chemotherapy . The study involved 188 children and young people aged one to 24, taken from 25 UK paediatric cancer centres between 2020 and 2024, having less intensive chemotherapy before transitioning to blinatumomab, a targeted immunotherapy designed to tell the immune system to attack leukaemia cells. The new approach achieved remission rates of 92 per cent, while long-term survival (82 per cent after three years) was comparable to children on more intensive traditional treatment plans.…