Joshua Kushner’s Thrive Capital has taken a stake in Shopify Inc., according to people familiar with the matter, marking a rare bet by the venture firm on a public company.

Thrive, best known for backing startups like OpenAI, informed its stakeholders that it has invested about $100 million in the e-commerce company, said one of the people, who spoke on condition of anonymity as the information is not public. The investment is framed as a bet on how artificial intelligence could lead to gains in commerce, said the people.