In the comic book "Deadpool's Secret Secret Wars", it is revealed that Deadpool is the first person to bond with the Venom Symbiote. Since we know Venom left a version of himself (an off-spring or just a part of his body) in the MCU, it could be possible for them to bring that (current) loose end into Avengers: Secret Wars. I think it would be a really funny nod to this comic run if they let Deadpool bond with Venom before eventually bonding with Spider-Man, or an MCU Eddie Brock.

What do you think?