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Super-resolution microscopy provides real-time picture of bacteria degrading biomass with enzyme complexes

phys.org·Erik F. Ringle·20 days ago
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Using a clustering algorithm and machine learning, a team of researchers analyzed 15,000 images of nearly 125 Clostridium thermocellum bacteria. The result is data-rich pictures showing the location of cellulosomes. Here, areas in yellow, green, and red show where cellulosomes are clustered on plant biomass particles (shaded in purple). The white rod-like shapes in the left photo are the bacteria. Credit: John Yarbrough, National Laboratory of the Rockies To the untrained eye, they look like blobs blotching the otherwise smooth surface of rod-like bacteria. But if you ask a microbiologist about "cellulosomes," they will likely tell you that those blobs are actually sophisticated cellulolytic machines.…

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