PITTSBURGH — Pittsburgh Pirates pitcher Paul Skenes came into his start against the St. Louis Cardinals looking for his first win against a team he's faced a number of times prior. Skenes wouldn't do that, as he gave up four earned runs over five innings of work and a career-high eight hits in the eventual 10-5 loss to the Cardinals at PNC Park on April 30. He also gave up two home runs, marking just the fourth time he's done that in the major leagues and the first time since Aug. 12, 2025 against the Milwaukee Brewers at American Family Field. Skenes had a great April coming into this outing, but the Cardinals got to him early and took advantage in the win. Skenes' Issues vs. the Cardinals Since MLB Debut Skenes has faced the Cardinals seven times over his three seasons in the major leagues and has lost five of those games.…