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AlphaGenome: AI for better understanding the genome
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AlphaGenome: AI for better understanding the genome

Google DeepMind·Ziga Avsec and Natasha Latysheva·about 1 month ago
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Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API. Update January 2026: This research has been published in Nature. You can read the full paper here and access the model here . The genome is our cellular instruction manual. It’s the complete set of DNA which guides nearly every part of a living organism, from appearance and function to growth and reproduction. Small variations in a genome’s DNA sequence can alter an organism’s response to its environment or its susceptibility to disease. But deciphering how the genome’s instructions are read at the molecular level — and what happens when a small DNA variation occurs — is still one of biology’s greatest mysteries.…

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