You’ve probably heard the anti-meth ad campaign slogan before: “Meth: Not Even Once.” The idea is that doing meth just one time can potentially ruin your life, which, given what little I know about meth, it does not seem like a casual thing you do to blow off some steam from time to time. It’s a lifetime commitment, for as short as that lifetime may be because of it. While that may ring true for methamphetamine, newer research suggests a very different story when it comes to psychedelics like psilocybin, the active compound in magic mushrooms . A study published in Nature Communications found that a single controlled dose of psilocybin may actually lead to measurable, and potentially positive, changes in the brain. Researchers observed these effects in healthy volunteers who had never taken psychedelics before, tracking both their brain activity and psychological state over time.…