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scRNA-seq batch correction UMAP integration

Reddit r/bioinformatics·u/shrubbyfoil·about 1 month ago
#wb65PCkR
#batch#correction#umap#donors#dataset#article

I want to get people's intuition if this dataset needs batch correction. It's single nucleus RNA sequencing of the human hippocampus across many donors. Some of the donors' cells are confined to corners of each cell type cluster on the UMAP.…

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