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#Degradation

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Retry isn't free: budget, amplification, and the cost that never shows up in p95
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Retry isn't free: budget, amplification, and the cost that never shows up in p95

DEV Community·Juan Torchia·17 days ago
#82uQJSwE

A reproducible experiment with Spring Boot 3, Java 21, and k6 to measure when retry actually buys availability and when it amplifies a failure. The metric that matters isn't p95: it's retry_amplification_factor.

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One drug, two cleanup crews: A built-in backup for targeted protein degradation
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One drug, two cleanup crews: A built-in backup for targeted protein degradation

Most drugs work by inhibition: they block a protein's activity but leave the protein itself intact. Targeted protein degradation takes a fundamentally different approach, harnessing the cell's own quality-control machinery to remove proteins entirely.

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‘Massive’ £200bn increase in funds needed to stop land around world turning to dust, UN warns
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‘Massive’ £200bn increase in funds needed to stop land around world turning to dust, UN warns

The Independent·Nick Ferris·26 days ago
#CNRw4hmn
#comments#land#unccd#fouad#degradation#world

Exclusive: Some £260bn is required annually to tackle the escalating problem, with only £56bn currently mobilised – with an increasing risk of forced migration, conflict and hits to food chains that impact billions of people

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Crab shell by-products could help regulate the marine lifetime of biodegradable plastics
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Crab shell by-products could help regulate the marine lifetime of biodegradable plastics

phys.org·Gunma University·about 1 month ago
#6dX4vuMQ

Biodegradable plastics hold potential for reducing marine plastic pollution, but degrade too quickly, limiting their practical use. Researchers from Gunma University now show that crab shell by-products can reduce the breakdown rate of biodegradable…

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I Almost Cancelled Claude: I Ran My Own Benchmarks Before Pulling the Trigger
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I Almost Cancelled Claude: I Ran My Own Benchmarks Before Pulling the Trigger

DEV Community·Juan Torchia·about 1 month ago
#3Cy243ES

874 points on HN for 'I cancelled Claude'. Before joining the chorus, I ran my own regression cases against real Claude Code logs. The degradation is real — just not where everyone's complaining about it.

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